Dual specificity protein phosphatase cdc14a

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August undefined, 2024

WebATR-Chk1-mediated protein degradation of Cdc25A protein phosphatase is also a mechanism conferring intra-S-phase checkpoint activation. Class Cellular Processes; Cell growth and death

CDC14A - Wikipedia

WebApr 23, 2024 · Dual-specificity protein phosphatases comprise a protein phosphatase subfamily with selectivity towards mitogen-activated protein (MAP) kinases, also named MKPs, or mitogen-activated protein kinase (MAPK) phosphatases. As powerful … WebDual specificity protein phosphatase CDC14A EC number EC:3.1.3.16 ( UniProtKB ENZYME Rhea) EC:3.1.3.48 ( UniProtKB ENZYME Rhea) Alternative names CDC14 cell division cycle 14 homolog A Gene names Name CDC14A Organism names Organism … allegra lacomini

Dual-Specificity Phosphatase Regulation in Neurons and Glial Cells

WebHuman Cdc14A is an evolutionary conserved dual-specificity protein phosphatase that reverses the modifications effected by cyclin-dependent kinases and plays an important role in centrosome duplication and mitotic regulation. WebFeb 25, 2009 · DUSPs can be divided into six subgroups on the basis of sequence similarity that include slingshots, PRLs (phosphatases of regenerating liver), Cdc14 phosphatases (Cdc is cell division cycle), PTENs (phosphatase and tensin homologues deleted on … http://cplm.biocuckoo.org/show.php?entry=Fr832EPWKvZIZEXxZc7&id=20493 allegra lab

dual specificity protein phosphatase CDC14A isoform 2

DUSP1 Gene - GeneCards DUS1 Protein DUS1 Antibody

WebMar 15, 2009 · DUSPs (dual-specificity phosphatases) are a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues within the one substrate. DUSPs have been … WebThe protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly s imilar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and … allegra lactationWebDual specificity protein phosphatase 2 is an enzyme that in humans is encoded by the DUSP2 gene. The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. … allegra lancaster

"WebAug 3, 2024 · Li et al. (1997) found that recombinant CDC14A exhibited the kinetic properties of dual-specific phosphatases (see 602038) in vitro.Plasmids expressing CDC14A specifically rescued the cell cycle-arrest phenotype of a cdc14 mutant yeast strain. Li et al. (1997) stated that the structural and functional equivalence of the yeast and … " - Dual specificity protein phosphatase cdc14a

Dual specificity protein phosphatase cdc14a

8556 - Gene ResultCDC14A cell division cycle 14A

WebCDC14A. Status. UniProtKB unreviewed (TrEMBL) Organism. Homo sapiens (Human) Amino acids. 565. Protein existence. Evidence at protein level. Annotation score. 3/5. ... PTHR23339 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE 1 hit; PROSITE. View protein in PROSITE; PS00383 … WebJan 27, 2024 · CDC14 encodes an essential highly conserved dual specificity protein phosphatase that in budding yeast Saccharomyces cerevisiae promotes mitotic exit, the transition from mitosis into G1 phase, and cytokinesis (Taylor et al., 1997).During most of the cell cycle, S. cerevisiae Cdc14 is entrapped in the nucleolus by complex formation …

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WebMar 21, 2024 · Entrez Gene Summary for CDC14A Gene. The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in … TP53 (Tumor Protein P53) is a Protein Coding gene. Diseases associated with … ECT2 (Epithelial Cell Transforming 2) is a Protein Coding gene. Diseases … VCAM1 (Vascular Cell Adhesion Molecule 1) is a Protein Coding gene. Diseases … CCNA1 (Cyclin A1) is a Protein Coding gene. Diseases associated with CCNA1 … CALM2 (Calmodulin 2) is a Protein Coding gene. Diseases associated with CALM2 … MAPK1 (Mitogen-Activated Protein Kinase 1) is a Protein Coding gene. Diseases … AURKA (Aurora Kinase A) is a Protein Coding gene. Diseases associated with … ATR (ATR Serine/Threonine Kinase) is a Protein Coding gene. Diseases … WebJan 1, 2010 · The activity of Cdc14p, an oligomeric dual specificity protein phosphatase from Saccharomyces cerevisiae, is required for cell cycle progression. J Biol Chem, 272 (1997), pp. 24,054-24,063. ... Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation. Nat Cell Biol, 4 (2002), pp. 318 …

WebApr 10, 2024 · dual specificity protein phosphatase CDC14A isoform 2 Download Models. Job ID Status Method Username Target Length Date (PST) Expiration Date (PST) 505201: Complete: Structure prediction : sabdus: dual specificity protein ... 623: 10 Apr 2024: 25 May 2024: 1 . 10 . 20 . 30 . 40 . 50 . 60 . 70 . 80 . ... WebDual specificity protein phosphatase CDC14A . Protein Synonyms/Alias. CDC14 cell division cycle 14 homolog A . Gene Name. CDC14A . Gene Synonyms/Alias . Created Date. July 27, 2013 . ... Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. May dephosphorylate the APC subunit …

WebSep 1, 2010 · Dual-specificity phosphatases (DUSPs) are a heterogenous group of phosphatases that belong to the PTP superfamily. The unique feature that characterizes DUSPs is their ability to dephosphorylate both phosphotyrosine and … WebApr 1, 2009 · CDC14 is a dual-specificity phosphatase that reduces CDK1 activity and reverses the actions of CDK1 during mitosis. In budding yeast, Cdc14 is essential for meiosis, but it is not known whether its mammalian …

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WebMar 9, 2024 · dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B. GeneRIFs: Gene References Into Functions. ... which occurred only at late passages when Cdc14A levels were low. Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription; allegra lanziWebDec 8, 2024 · The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. ... Human phosphatase CDC14A … allegra laneWebPR:000005184 dual specificity protein phosphatase CDC14A (term hierarchy) EC. 3.1.3.16, 3.1.3.48. InterPro Domains. ... IPR020422 Dual specificity protein phosphatase domain. IPR029260 Dual specificity/tyrosine protein phosphatase, N-terminal. IPR016130 Protein-tyrosine phosphatase, active site. IPR003595 Protein-tyrosine … allegra k pea coat