Webprofoundly aggravated in iron-loaded ApoE-/-FPNwt/C326S mice, suggesting a pro-atherogenic role for iron. Iron heavily deposits in the arterial media layer, which … WebAnalysis of the bone formation rate at the tibia showed no difference in both genotypes, but it was reduced in the vertebral bone of Fpn C326S [36%, p < 0.05] compared to WT mice. Serum levels of the bone formation marker, P1NP, were significantly reduced in both, Hfe-/-and Fpn C326S compared with WT mice [Hfe-/-, 35%; Fpn C326S, 40%; p

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WebWe demonstrated that features associated with T2DM in Leprdb/db mice, such as obesity, steatosis, or IR, reduce the degree of tissue iron overload in Fpnwt/C326S mice, suggesting an 'iron resistance' phenotype. Conversely, we observed increased serum iron levels that strongly exceeded those in the iron-overloaded Fpnwt/C326S mice. WebJan 1, 2024 · Europe PMC is an archive of life sciences journal literature. how do jellyfish communicate with each other

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