WebMeth excretion and organic cation transporters (OCTs) and multidrug and toxin extrusion (MATE) transporters. ... organic anion transporter (OAT) or MATE. Some of … Web1. Multidrug and toxic compound extrusion (MATE)-type transporters, which were first identified as a bacterial drug transporter family, are present in almost all prokaryotes …

Export of Salicylic Acid from the Chloroplast Requires the …

Web1 aug. 2016 · Multidrug and toxin extrusion transporters (MATEs) have a determining influence on the pharmacokinetic profiles of many drugs and are involved in several clinical drug-drug interactions (DDIs). Web22 ian. 2013 · The human multidrug and toxin extrusion (MATE) transporter 1 contributes to the tissue distribution and excretion of many drugs. Inhibition of MATE1 … fulton county georgia gis mapping

Associations of genetic polymorphisms of the transporters organic ...

WebExtrusion of antimicrobial compounds by bacterial multidrug efflux pumps is a of the major causes of failure of drug-based treatments as bacteria can evade the effects of multiple structurally different compounds simultaneously. However, very little is currently known about the function and substrate range of these efflux pumps. Web1 dec. 2024 · MATE (multidrug and toxic compound extrusion) is a large family of secondary active transporters involved in the transport of various compounds across … Web12 apr. 2024 · The target drug transporters assessed were P-glycoprotein (P-gp), breast cancer resistance protein (BCRP), organic anion transporting polypeptide (OATP) 1B1, … gips admin building